Pitolisant hydrochloride ( Ciproxidine;BF 2649;BF2649;BF-2649 )

Catalog No. M16495 CAS No. 903576-44-3

A potent and selective antagonist of H3 receptor with Ki/EC50 of 0.16/1.5 nM.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
5MG	39	In Stock
10MG	61	In Stock
25MG	113	In Stock
50MG	186	In Stock
100MG	295	In Stock
200MG	443	In Stock
500MG	708	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

Pitolisant hydrochloride
Note

Research use only, not for human use.
Brief Description

A potent and selective antagonist of H3 receptor with Ki/EC50 of 0.16/1.5 nM.
Description

A potent and selective antagonist of H3 receptor with Ki/EC50 of 0.16/1.5 nM; no effect on H1, H2, H4 receptors (IC50>10 uM); orally bioactive.Sleep Disorder Approved
Synonyms

Ciproxidine;BF 2649;BF2649;BF-2649
Pathway

GPCR/G Protein
Target

Histamine Receptor
Recptor

Histamine Receptor
Research Area

Neurological Disease
Indication

Sleep Disorder

Chemical Information

CAS Number

903576-44-3
Formula Weight

332.31
Molecular Formula

C17H27Cl2NO
Purity

>98% (HPLC)
Solubility

DMSO: ≥ 43 mg/mL
SMILES

C1CCN(CC1)CCCOCCCC2=CC=C(C=C2)Cl.Cl
Chemical Name

Piperidine, 1-[3-[3-(4-chlorophenyl)propoxy]propyl]-, hydrochloride (1:1)

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Ligneau X, et al. J Pharmacol Exp Ther. 2007 Jan;320(1):365-75.
2. Dudek M, et al. Metab Brain Dis. 2016 Oct;31(5):1023-9.
3. Ligneau X, et al. Biochem Pharmacol. 2007 Apr 15;73(8):1215-24.

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